Share This
Faculty and Staff Profiles

Luis Cardoso

Assistant Professor

School/Division

Grove School of Engineering

Department

Biomedical Engineering

Office

Steinman Hall T-431

p: 212.650.7154

f: 212.650.6727

e: cardoso@engr.ccny.cuny.edu

  • Education

    Postdoc, Department of Orthopaedics, Mount Sinai School of Medicine, New York, NY 2004-2005  

    Ph.D., Biomechanics, Paris University, France, 2003 Master, Biomechanics, Paris University, France, 1999  

    B.S., Biomedical Engineering, National Polytechnic Institute, Mexico City, Mexico, 1996

  • Research Interests

    Research in bone quality, integrating musculoskeletal biomechanics, signal/images processing, bioinstrumentation and mechanotransduction in bone. Research in bone biomechanics includes studies of bone mineral density, microarchitecture and bone tissue quality at the microscopic and macroscopic levels. Experimental, theoretical and numerical approaches are combined for this purpose. Bone mechanical properties are evaluated from analysis of 3D images of cancellous bone, ultrasound wave propagation, mechanical tests and Finite Element Modeling. In particular, we are interested in assessing changes in the mechanical properties of cancellous bone after disuse with and without anti-resorptive therapy using ultrasound and 3D images from microCT scanning. Design of an Ultrasound device for assessment of bone quality ex vivo and in vivo. Theoretical studies in poroelasticity and the interaction between wave propagation and porous media Mechanotransduction of osteocytes in bone using animal model

  • Publications

    • Cardoso, L; Meunier, A. and Oddou, C. “In vitro acoustic wave propagation in human and bovine cancellous bone as predicted by the Biot’s theory”. Journal of Mechanics in Medicine and Biology, Vol. 8, No. 2 (2008) pp.1-19  

    • Vengrenyuk, Y; Cardoso, L. and Weinbaum, S. “Micro-CT Based Analysis of a New Paradigm for Vulnerable Plaque Rupture: Cellular Microcalcifications in Fibrous Caps” Molecular & Cellular Biomechanics, Special issue in honor of Prof. Y. C. Fung’s 90th Anniversary, Vol. 5, No. 1, (2008) pp. 37-48  

    • Choi, B. G; Vilahur, G. Cardoso, L. Fritton, J. C. Ibanez, B. Zafar, M. U. Yadegar, D. Speidl, W. S. Schaffler, M. B. Fuster, V. Badimon J. J. “Ovariectomy increases vascular calcification via the OPG/RANKL cytokine signalling pathway”. Eur J Clin Invest 2008; 38 (4): 211–217  

    • Choi, B. G; Vilahur, G; Zafar, M. U; Cardoso, L; Yadegar, D; Ibanez, B; Tunstead, J; Viles-Gonzalez, J. F; Schaffler, M. B; Fuster, V; Badimon, J. J. “Selective estrogen receptor modulation influences atherosclerotic plaque composition in a rabbit menopause model” Atherosclerosis (2008) doi:10.1016/j.atherosclerosis.2008.01.017 

    • Sun, L; Peng, Y; Sharrow, AC; Iqbal, J; Zhang, Z; Papachristou, DJ; Zaidi, S; Zhu, LL; Yaroslavskiy, BB; Zhou, H; Zallone, A; Sairam, MR; Kumar, TR; Bo, W; Braun, J; Cardoso-Landa, L; Schaffler, MB; Moonga, BS; Blair, HC; Zaidi, M. FSH Directly Regulates Bone Mass. CELL, 125 (2): 247-260 APR 21 2006 ISSN: 0092-8674 

    • Cardoso, L., Teboul, F., Sedel, L., Meunier, A. and Oddou, C. In Vitro Acoustic Waves Propagation in Human and Bovine Cancellous Bone. Journal of Bone and Mineral Research. 2003 Oct; 18(10): 1803-12. 

    • Cardoso, L., Teboul, F., Meunier, A. and Oddou, C. Ultrasound Characterization of Cancellous Bone: Theoretical and Experimental analysis. Transactions of the Ultrasonics Symposium, 2001 IEEE, vol. 2: 1213-16. 

    • Cardoso, L., Gallegos, V., Rule, R. and Suriano, H. The development of the biomedical engineering in Mexico (Estudio del desarrollo de la Ingenieria Biomedica en Mexico). Gaceta Medica de Mexico, 1995, vol. 131: 46-48. Peer reviewed conferences 

    • Yuliya Vengrenyuk; Luis Cardoso; and Sheldon Weinbaum, "Micro-CT based analysis of a new paradigm for vulnerable plaque rupture" at the 6th International Conference on Medical Innovations, in Vienna, Austria May 30-31, 2008. (2008 Mimics Innovation Award) 

    • Gailani, G; Cardoso, L. & Cowin S.C. “Experimental determination of osteon permeability”. 9th International Bone Fluid Flow Workshop. Bone Fluid Flow, Adaptation, and Regeneration. May 22 and 23, 2008. Vrije Universiteit, Amsterdam, "Collegezaal OZW" 

    • Vengrenyuk, Y; Schaffler M. B. & Cardoso, L. “Poroelastic media approach of ultrasound wave propagation applied to bone undergoing disuse-induced osteoporosis”. IEEE International Ultrasonic Symposium 2007, New York, NY

    • Gu, X; Leong, D; Li, Y.H; Guzman, F; Sun H. B; and Cardoso, L. Computer-Controlled Joint Loading System For Biomechanics Research In A Rat Model. 2007 Annual Biomedical Engineering Society Meeting, Los Angeles, CA 

    • Vengrenyuk, Y; Cardoso, L; Carlier, S.G; Einav, S. Fallon, J.T; Randolph, G.J. & Weinbaum, S. “Micro-CT Based Finite Element Analysis of Atherosclerotic Plaque Stability”. 2007 Annual Biomedical Engineering Society Meeting, Los Angeles, CA 

    • Vengrenyuk, Y; Cardoso, L; and Weinbaum S. “Micro-CT Based Analysis of A New Paradigm For Vulnerable Plaque Rupture”. Fifth International Bio-Fluid Symposium and Workshop March 28-30, 2008, Pasadena, California Under the Auspices of the US National Committee on Biomechanics (USNCB) The Biomedical Engineering Society (BMES) International Federation for Medical and Biological Engineering (IFMBE) 

    • Herman, B. C.; Cardoso , L.; Majeska, R. J. and Schaffler, M B. “The Importance of Early Apoptotic Events Following Microdamage In Triggering Fatigue Induced Bone Remodeling”. 53rd Annual Meeting of the Orthopaedic Research Society, Feb 11-14 2007, San Diego Cal. 

    • Herman, B C; Laudier, D M; Cardoso-Landa, L; Zhu, L-L; Li, Y; Majeska R J; Sun, H B; Schaffler, M B B. C.; Cardoso , L.; Majeska, R. J. and Schaffler, M B. “Acute osteocyte response to Fatigue Microdamage: Production of HIF-1 and VEGF-”. 53rd Annual Meeting of the Orthopaedic Research Society, Feb 11-14 2007, San Diego Cal. 

    • Yuliya Vengrenyuk, Luis Cardoso Landa, Stéphane Carlier, Momina Andrabi1, Savvas Xanthos, Renu Virmani and Sheldon Weinbaum. “Vulnerable plaque rupture due to stress concentration around cellular level calcifications in the fibrous cap”. Abstract in CD ROM Annual Biomedical Engineering Society Meeting 2006, Chicago, IL 

    • Cardoso, L; Laudier, D M; Majeska, R; Schaffler, M B. Inhibition of osteocyte apoptosis prevents activation of bone remodeling after fatigue in vivo. (2006 ORS New Investigator Research Award). Abstract in CD ROM “52nd annual meeting of the Orthopaedic Research Society, Chicago, USA”, March 19-22, 2006 

    • Yuliya Vengrenyuk, Luis Cardoso Landa, Stéphane Carlier, Momina Andrabi, Savvas Xanthos, Renu Virmani and Sheldon Weinbaum. “MicroCT assessment of minute cellular level calcifications in fibrous cap as a cause of vulnerable plaque rupture”. Abstract in CD ROM American Heart Association meeting 2006

    • Brian G. Choi, Gemma Vilahur, M. Urooj Zafar, Luis Cardoso, Daniel Yadegar, Juan F. Viles-Gonzalez, Mitchell B. Schaffler, Valentin Fuster, Juan J. Badimon. "Selective Estrogen Receptor Modulation Reduces Characteristics of Plaque Vulnerability". DOM Research Evening, the New York Academy of Medicine, May 31st 2006 

    • BG Choi, G Vilahur, MU Zafar, L Cardoso, CA Novoselsky, D Yadegar, B Bonacasa, JF Viles-Gonzalez, MB Schaffler, V Fuster, JJ. " Atherosclerosis regression with selective estrogen receptor modulator therapy: an in vivo study of raloxifene by magnetic resonance imaging and micro-computed tomography. Abstract in CD ROM 55th Annual Scientific Session of the American College of Cardiology. Atlanta, GA, March 2006

    • Herman, B C; Cardoso, L; Jepsen, K J; Schaffler, M B Recovery of Stiffness Loss Following In Vivo Fatigue Loading. Abstract in CD ROM “52nd annual meeting of the Orthopaedic Research Society, Chicago, USA”, March 19-22, 2006 

    • Yuliya Vengrenyuk, Savvas Xanthos, Stéphane Carlier, Luis Cardoso Landa, Frank Kolodgie, Lane Gilchrist, Peter Ganatos, Renu Virmani, Shmuel Einav and Sheldon Weinbaum. “New hypothesis for vulnerable plaque rupture: interfacial stress concentration induced debonding of calcified macrophages in the thin fibrous cap”. Abstract in CD ROM 5th World congress in Biomechanics. Germany 2006

    • Cardoso, L; Seo, S; Jepsen, K J; Schaffler, M B. Ultrasound based assessment of trabecular bone in disuse osteoporosis . Abstract in “Bone Loss during Spaceflight, Cleveland, USA”, June 23-24, 2005

    • Cardoso, L; Seo, S; Jepsen, K J; Oddou, C; Meunier, A; Schaffler, M B. Ultrasonic characterization of anisotropic trabecular bone undergoing disuse osteoporosis with and without antiresorptive therapy. Abstract in CD ROM “51st annual meeting of the Orthopaedic Research Society, Washington, USA”, February 20-23, 2005

    • Cardoso, L; Seo, S; Jepsen, K J; Oddou, C; Meunier, A; Schaffler, M B. Structurally-based ultrasonic approach of cancellous bone characterization. Abstract in CD ROM “51st annual meeting of the Orthopaedic Research Society, Washington, USA”, February 20-23, 2005 

    • Cardoso, L., Meunier, A; Oddou, C. Sondage Ultrasonore et Caractérisation des Tissus Biologiques. Abstract in “Journées Extensométrie 2003, Champs-Sur-Marne, France”, 2003 

    • Cardoso, L; Meunier, A; Oddou, C. Theoretical and Experimental Ultrasonic Characterization of Anisotropic Properties in Cancellous Bone. Abstract in “World Congress on Ultrasonics, Paris, France”, 2003 

    • Cardoso, L; Teboul, F; Sedel, L; Oddou, C; Meunier, A. Ultrasonic characterization of human and bovine trabecular bone using Biot theory . Abstract in CD ROM “49th annual meeting of the Orthopaedic Research Society, New Orleans, USA”, February 2-5, 2003 

    • Cardoso, L; Teboul, F; Meunier, A; Oddou, C. Theoretical and experimental approach in ultrasonic characterization of cancellous bone. Abstract in “16ème Congrès Français de Mécanique, Nice, France”, 2003

    • Cardoso, L; Teboul, F; Oddou, C; Meunier, A. Ultrasonic Wave Propagation in Human and Bovine Cancellous Bone. Abstract in “IUTAM Symposium on the Mechanics of Physicochemical and Electromechanical Interactions in Porous Media, Eindhoven, Netherlands”, 2003

    • Cardoso, L; Teboul, F; Meunier, A; Oddou, C. Dynamics of Porous Media ans Acoustical characterization of bony Tissue. Abstract in “12th International Conference on Mechanics in Medicine and Biology, Lemnos, Greece”, 2002

    • Cardoso, L; Teboul, F; Meunier, A; Oddou, C. Characterisation of Cancellous Human Bone Properties by Ultrasonics. “Proceedings of the 13th Conference of the European Society of Biomechanics,Wroclaw, Poland” Abstract in “Acta of Bioengineering and Biomechanics”. Vol 4, sup 1, pp 367-368, 2002 

    • Cardoso, L; Teboul, F; Meunier, A; Oddou, C. Ultrasound Wave Propagation in Porous Medium : Application to Cancellous Bone. Abstract in CD ROM “IV World Congress of Biomechanics, Calgary, Alberta, Canada”, 2002 

    • Cardoso, L; Teboul, F; Meunier, A; Oddou, C. Ultrasound Characterization of Cancellous Bone: Theoretical and Experimental analysis. Abstract in “2001 IEEE International Ultrasonics Symposium and the World Congress on Ultrasonics, Atlanta, Georgia”, pp125-126, 2001 

    • Cardoso, L; Teboul, F; Meunier, A; Oddou, C. Trabecular bovine bone characterization by ultrasound. Poroelastic approach. “XXVIème Congrès de la Société de Biomécanique. Marseille, France”.Abstract in Archives of Physiology and Biochemistry Vol 109, p. 96, Suppt Sep 2001 

    • Cardoso, L; Teboul, F; Meunier, A; Oddou, C. Acoustique des milieux poreux: Application à la caractérisation de l'os trabeculaire (Porous media acoustics. Application to the cancellous bone characterization). Abstract in CD ROM “XVème Congrès Français de Mécanique, Nancy, France. Num 311, pp1-7” 2001 

    • Cardoso, L; Teboul, F; Meunier, A; Oddou, C. Acoustique Ultrasonore appliqué à l'Os Trabeculaire (Ultrasonic acoustics applied to cancellous bone). Abstract in “VIIème Journées d'Acoustique Physique, Sous-Marine et Ultrasonore. Marseille, France. ” 2001 

    • Oddou C; Cardoso L; Meunier A; Geiger D. A Critical Analysis of the Ultrasound Technique for Bone Tissue Rheological Characterization. Abstract in “The Second China-Denmark-France Symposium on Biomechanics and Biorheology. Shanghai, China.” 2000

<< Back To Directory