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Faculty and Staff Profiles

Carol Moore

Medical Professor

School/Division

Sophie Davis School of Biomedical Education

Department

Office

Harris Hall 210

p: 212-650-6926

f: 212-650-7583

e: moore@med.cuny.edu

  • Education

    B.S., 1965, Ohio State University

    M.S., 1969, Ph.D., 1970, Pennsylvania State University
  • Research Interests

    • Using a yeast model for studying human disease mechanisms.

    • DNA repair mechanisms and their relationship to human diseases.

    • Genetic control of cellular responses to ionizing radiation and radiomimetic anticancer drugs.

    • Targeting AIDS fungal pathogens by mutant approaches. 
  • Publications

    • Ovalle, R., S.T. Lim, B. Holder, C.K. Jue, C.W. Moore, and P.N. Lipke 1998. A spheroplast rate assay for determination of cell wall integrity in yeast. Yeast 14:1159-1166.

    • Moore, C.W. 1999. Bleomycin. pp. 292-297 In: Encyclopedia of Molecular Biology, John Wiley and Sons, New York.

    • Moore, C. W., J. Mc.Koy, M. Dardalhon, D. Davermann, M. Martinez, and D. Averbeck 2000. DNA damage-inducible and RAD52-independent repair of DNA double-strand breaks in Saccharomyces cerevisiae. Genetics 154:1085-1099.

    • Febres, D. E., A. Pramanik, M. Caton, K. Doherty, J. Mc.Koy, E. Garcia, W. Alejo, and C. W. Moore. 2001. The novel BLM3 gene encodes a protein that protects against lethal effects of oxidative damage. Cellular and Molecular Biology 47:1149-1162.

    • Davermann, D., M. Martinez, N. Patel, J. McKoy, D. Averbeck, and C. W. Moore, 2002. Impaired mitochondrial function protects against free radical-mediated cell death. Free Radical Biology and Medicine33:1209-1220.

    • Anyatonwu, G., E. Garcia, A. Pramanik, M. Powell, and C. W. Moore. 2003. Meiotic and mitotic phenotypes conferred by the blm1-1 mutationand MSH4 suppression in Saccharomyces cerevisiae. International Journal of Molecular Sciences, 4:1-12.

    • Moore, C.W., J. McKoy, R. Del Valle, D. Armstrong, E. M. Bernard, N. Katz, and R. E. Gordon, 2003. Fungal cell wall septation and cytokinesis are inhibited by bleomycins. Antimicrobial Agents and Chemotherapy 47:3281-3289.

    • Martinez, M., A. Pramanik, S. M. Ndje, C. W. Moore. 2003. Overexpression of genes involved in vesicular trafficking to the vacuole defends against lethal effects of oxidative damage. Cellular and Molecular Biology 49:1025-1035.

    • Martinez, M., A. Pramanik, J. McKoy, K. Robert, C. W. Moore. 2003. Pleiotrophic cellular deficiencies conferred by the blm5-1 mutation of Saccharomyces cerevisiae. Cellular and Molecular Biology 49:1049-1056.

    • Doherty, K., A. Pramanik, L. Pride, J. Lukose, and C.W. Moore. 2004. Expression of the expanded YFL007w ORF and assignment of the gene name BLM10. Yeast 21:1021-1023.




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