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Sophie Davis School of Biomedical Education

Pathobiology Course Descriptions

  • MED 20400
Molecules to Cells I
Spring, 2nd Year, 4 credits
4 sessions per week
Duration: 15 weeks
Prerequisites: MED 10200, MED 20300, BIO 20600 and BIO 20700.
Course Director: Serafin Piñol-Roma, Ph.D.
This two semester course (MED 20400 and 30500) is designed to provide students with comprehensive and integrated concepts of biochemistry, cell biology, and medical genetics within a clinically oriented framework. Topics are presented with the aim that students will become aware of the contributions of cell and molecular biology and genetics to future developments in clinical diagnosis and treatment. Students are expected to acquire the necessary skills to integrate microscopic structure and cellular function, a prerequisite for other disciplines such as Human Development, Medical Histology, Physiology, Immunology, Pathophysiology, and other related areas. Sessions include lectures, small group discussions, and clinical correlations.

 

  • MED 30500
Molecules to Cells II
Fall, 3rd Year, 3 credits
5 sessions per week
Duration: 15 weeks
Prerequisites: MED 20400.
Course Director: Serafin Piñol-Roma, Ph.D.
This two semester course (MED 20400 and 30500) is designed to provide students with comprehensive and integrated concepts of biochemistry, cell biology, and medical genetics within a clinically oriented framework. Topics are presented with the aim that students will become aware of the contributions of cell and molecular biology and genetics to future developments in clinical diagnosis and treatment. Students are expected to acquire the necessary skills to integrate microscopic structure and cellular function, a prerequisite for other disciplines such as Human Development, Medical Histology, Physiology, Immunology, Pathophysiology, and other related areas. Sessions include lectures, small group discussions, and clinical correlations.

 

  • MED 33602
Human Gross Anatomy, Human Development and Organ Imaging
Spring, 3rd Year/ 7 credits
16 hours per week (160 hours per semester)
Prerequisites: MED 20400 and 30500
Duration: 11 weeks (includes one week preparation for the National Board of Medical
Examiners - Gross Anatomy and Embryology Examination)
Course Director: Cigdem Erkuran Yilmaz, M.D., Ph.D.
The objective of the integrated Human Gross Anatomy and Human Development course is to provide students with hand on experience in the study of the structure and function of the human body, an understanding of relevant aspects of human development and its abnormalities, and the value of imaging techniques in the visualization of the human body. Structure at the macroscopic level is explored through lectures in gross anatomy and embryology coupled with detailed regional dissections. Students are expected to examine anatomic relationships leading to an integration of anatomic function and embryo-fetal development under normal and pathologic conditions.

 

  • MED 33603
Histology and Cell Biology
Spring, 3rd Year/ 4 credits
16 hours per week (80 hours per semester)
Prerequisites: MED 20400 and 30500
Duration: 6 weeks (includes one week preparation for the National Board of Medical
Examiners - Histology and Cell Biology Examination)
Course Director: Abraham L. Kierszenbaum, M.D., Ph.D.
Histology pursues an extension of topics presented in the Molecules to Cells and Human Gross Anatomy-Embryology courses. The main objective is the microscopic identification of cells, tissues, and organs in preparation for the study of normal and abnormal function in further courses on systemic function and pathology. Students are expected to master the material by acquiring concept mapping and critical analysis skills by integrating structural, molecular and functional views of cell and molecular biology and human development through clinical and pathologic examples. This approach intends to highlight the impact of cell and molecular biology in preventive medicine and disease.

 

  • MED 48801
Host Defense, Infection, and Pathogenesis (Step 8)
Spring, 4th Year, 10 credits
20 hours per week (248 hours per semester)
Duration: 13.4 weeks (includes one week preparation for the National Board of Medical
Examiners - Microbiology Examination)
Prerequisites: MED 30500 and MED 33602
Course Director: Sanna Goyert, Ph.D.
This course integrates the biomedical disciplines of immunology and medical microbiology with the pathophysiology of infectious and/or immunological diseases and the appropriate pharmacology, emphasizing the relevance to the clinical setting. Students learn fundamental concepts and terminologies of immunology, bacteriology, virology, parasitology and mycology with an emphasis on mechanisms of microbial disease transmission, interwoven with an understanding of host defense mechanisms. A basic understanding of the classification and characteristics of infectious microorganisms, the mechanisms by which infectious agents cause disease, and methods of both prevention and treatment are highlighted. Causes and treatment of immune diseases are also emphasized. Students become familiar with the concepts of inflammation, sepsis, cell injury, tissue repair, hemodynamic disorders, genetic disorders, environmental and nutritional pathology, immunodeficiency diseases, autoimmune diseases, allergy, metabolic diseases and neoplasia.
Throughout the course, small group tutorials and interactive clinical correlations based on clinical cases link basic science concepts to clinical medicine. Laboratories in microbiology and immunology introduce students to some of the basic techniques used in diagnostic laboratories for the identification of infectious bacteria, parasites and fungi, and acquaint students with laboratory tests that are routinely performed in diagnostic clinical microbiology and immunology laboratories. Laboratories also utilize diagnostic unknowns to train students in the interpretation of clinical case histories and the isolation and characterization of microorganisms involved in infectious diseases. General pathology laboratories focus on observations of gross specimens and light microscopic examination of diseased tissues to identify the features of general pathological processes relevant to diverse disease states. Tutorials, clinico-pathological correlations and laboratories emphasize problem-solving skills, integration of knowledge and independent learning.

 

  • PA 39100
Microbiology
4 credits/45 lecture hours and 45 laboratory hours (6 hrs/wk)
Course Director: Viera Lima, D.D.S.
This course is designed for physician assistant students and focuses on the roles of bacteria, fungi, viruses, rickettsiae, chlamydia, protozoa and parasites in disease, immunity, and public health practice. Lectures and laboratory exercises emphasize clinical applications and basic laboratory diagnostic procedures. Students become familiar with the types of organisms responsible for human disease, the mechanisms by which they produce disease, and the application of this knowledge to the treatment of patients.

 

  • MED 51902
Systemic Pathology I (Step 10)
Fall, 5th Year/5.5 credits
7 hours per week (119 hours per semester)
Prerequisite: MED 48801
Duration: 17 weeks
Course Director: Ahna M. Blutreich, M.D.
  • MED 51903
Systemic Pathology II (Step 10)
Spring, 5th Year/2 credits
5.5 hours per week (38 hours per semester)
Prerequisite: MED 51902
Duration: 8 weeks (includes one week preparation for the National Board of Medical
Examiners - Pathology Examination)
Course Director: Ahna M. Blutreich, M.D.
In the Systemic Pathology course, students learn to apply the principles and mechanisms of diseases. The course covers the disease process in all organ systems, including a separate section on the cardiovascular system, with the pertinent pathophysiologic correlations. The basic clinical aspects of systemic disease are introduced and correlated with the morphologic features of the diseases. The course utilizes lectures with kodachrome slides, power point presentations, essay assignments, laboratory sessions with gross specimens and pertinent clinical histories, microscopic slides, and review sessions.