Ph.D., 1970, Pennsylvania State University
M.S., 1969, Pennsylvania State University
B.S., 1965, Ohio State University
Using a yeast model for studying human disease mechanisms.
DNA repair mechanisms and their relationship to human diseases.
Genetic control of cellular responses to ionizing radiation and radiomimetic anticancer drugs.
Targeting AIDS fungal pathogens by mutant approaches.
Doherty, K., A. Pramanik, L. Pride, J. Lukose, and C.W. Moore. 2004. Expression of the expanded YFL007w ORF and assignment of the gene name BLM10. Yeast 21:1021-1023.
Martinez, M., A. Pramanik, J. McKoy, K. Robert, C. W. Moore. 2003. Pleiotrophic cellular deficiencies conferred by the blm5-1 mutation of Saccharomyces cerevisiae. Cellular and Molecular Biology 49:1049-1056.
Martinez, M., A. Pramanik, S. M. Ndje, C. W. Moore. 2003. Overexpression of genes involved in vesicular trafficking to the vacuole defends against lethal effects of oxidative damage. Cellular and Molecular Biology 49:1025-1035.
Moore, C.W., J. McKoy, R. Del Valle, D. Armstrong, E. M. Bernard, N. Katz, and R. E. Gordon, 2003. Fungal cell wall septation and cytokinesis are inhibited by bleomycins. Antimicrobial Agents and Chemotherapy 47:3281-3289.
Anyatonwu, G., E. Garcia, A. Pramanik, M. Powell, and C. W. Moore. 2003. Meiotic and mitotic phenotypes conferred by the blm1-1 mutationand MSH4 suppression in Saccharomyces cerevisiae. International Journal of Molecular Sciences, 4:1-12.
Davermann, D., M. Martinez, N. Patel, J. McKoy, D. Averbeck, and C. W. Moore, 2002. Impaired mitochondrial function protects against free radical-mediated cell death. Free Radical Biology and Medicine33:1209-1220.
Febres, D. E., A. Pramanik, M. Caton, K. Doherty, J. Mc.Koy, E. Garcia, W. Alejo, and C. W. Moore. 2001. The novel BLM3 gene encodes a protein that protects against lethal effects of oxidative damage. Cellular and Molecular Biology 47:1149-1162.
Moore, C. W., J. Mc.Koy, M. Dardalhon, D. Davermann, M. Martinez, and D. Averbeck 2000. DNA damage-inducible and RAD52-independent repair of DNA double-strand breaks in Saccharomyces cerevisiae. Genetics 154:1085-1099.
Moore, C.W. 1999. Bleomycin. pp. 292-297 In: Encyclopedia of Molecular Biology, John Wiley and Sons, New York.
Ovalle, R., S.T. Lim, B. Holder, C.K. Jue, C.W. Moore, and P.N. Lipke 1998. A spheroplast rate assay for determination of cell wall integrity in yeast. Yeast 14:1159-1166.