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Maribel Vazquez

Faculty and Staff Profiles

Maribel Vazquez

Associate Professor

School/Division
Department

Additional Departments/Affiliated Programs::

Office
Room 403-D/ ST-508 (Office/Lab)
Building: 
Steinman Hall
Phone Number: 
(212) 650-5209 (Office)
Secondary Phone: 
(212) 650-6634 (Lab)
Fax: 
(212) 650-6727
Email: 
vaZqueZ@ccny.cuny.edu
Personal Website: 
https://www.linkedin.com/in/maribel-vazquez-05304a139/
Dr. Vazquez in 2015
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About
Description: 

Dr. Vazquez is a Founding Member of the Department of Biomedical Engineering at CCNY, established in 2002 by a team of 4 faculty who worked tirelessly to develop the new undergraduate curriculum and program. She established a micro-nanofabrication laboratory using initial funding from Air Force Office of Scientific Research (AFOSR) to acquire key pieces of microfabrication equipment in collaboration with Chemical Engineering. Her Biomedical Engineering Research Laboratory is located in Steinman Hall, ST-508.

Her Research Laboratory integrates the design and manufacture of microfluidic systems and nanoparticles to examine the migration of neural progenitor cells and their implications in the health and development of the Nervous System. Research projects have utilized bio-microtechnologies to examine the development and dissemination of glial tumors, develop integrated cellular systems of glia and neurons for regenerative medicine, and to investigate progenitor migration during retinogenesis and retinal transplantation

Dr. Vazquez has served as Principal Investigator (PI) in research funding from the NIH (National Cancer Institute, National Institute of General Medical Sciences and National Eye Institute) and the NSF (CBET: Biomedical Engineering).  She has also as Co-PI on several educational initiatives from the National Science Foundation (NSF: Nanotechnology Education for Undergraduates, Emergent Behaviors of Intracellular Systems) and AFOSR (Microtechnology and Fabrication for Mechanical Engineers). 

Dr. Vazquez regularly Teaches Undergraduate and Graduate Laboratory-based Courses in Microfluidics and Microfabrication, BME Experimental Methods and Capstone/ Biodesign for BME Seniors and students in the Master's in Translational Medicine (MTM) program. 


 

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Education
Description: 

Massachusetts Institute of Technology (MIT) Cambridge, MA

Doctor of Science (Sc.D.), Mechanical Engineering, 2001


Massachusetts Institute of Technology (MIT)  Cambridge, MA

Master of Science (M.S.), Mechanical Engineering, 1996


Cornell University (Ithaca, NY)

Bachelor of Science (B.S.), Mechanical and Aerospace Engineering, 1992 


 

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Industry Experience
Description: 

Intel Corporation, Santa Clara, CA (Summer 1998, Summer 1997)

Mechanical Engineer, Clean Room Microcontamination


Intel Corporation, Portland, OR (Summer 1996)

Mechanical Engineer, Clean Room Facilities

Intel Corporation, Portland, OR (June 1992- Dec.1995)

Mechanical Engineer, General Site Services


NASA Research Center, Cleveland, OH (Summer 1991)

Mechanical Engineer, Cryogenics Division


 

Heading: 
Research Interests
Description: 

TECHNOLOGY:

Microfluidics-Based Biosystems    

Nanotechnology and Intracellular Imaging


BIOLOGY:

Cell Motility and Collective Migration

Glial and Neuronal Progenitor Biology

Neuromuscular Junction (NMJ)


CLINICAL:

Photoreceptor Transplantation

Health Disparities 


EDUCATION:

Health Disparities in Engineering Curricula

​Biodesign and Innovation 

Summer STEM Institute

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Keynote Recognition and Community Outreach
Description: 

2017 Keynote speaker at BCC Hidden Figures: Women in STEM Luncheon, Bronx Community College http://photosbywarrenkthompson.zenfolio.com/bcchiddenfigureswomeninstem11022017

2017 Invited Speaker at Gordon Research Conference in Microfluidics, Lucca (Barga) Italy: Microfluidics for the Visual System https://www.grc.org/programs.aspx?id=13022

2017 Winner of President's Award for Excellence: Recognizes CCNY faculty members for their innovative approaches in mentoring, research, teaching, scholarship and serving as exemplary models for excellence in scholarship, teaching and student success. https://www.ccny.cuny.edu/bme/news-0

2016 TEPTU Science Research Entrepreneurship for High School Students (Africa-US partnership, Judging Panel) http://www.teptu.com/

2015 Hispanic Outlook in Higher Education Magazine, CUNY Decade of Science (August 7, 2015)   http://www.hispanicoutlook.com/mary-ann-cooper/2015/8/7/hunter-college-cuny-celebrates-achievements-by-women-of-all-colors-in-decade-of-science

2013 Univision Televised Reporting (Channel 41), 'STEM and the Elusive Latina Role Model,' (August 12, 2013)     https://www.youtube.com/watch?v=UkHtpsgybXg

2013 New York City Council, Televised Panel Discussion led by State Senator Y. Rodriguez, 'CUNY Stem Initiatives,' September 17, 2013

2012 Hispanic Outlook in Higher Education Magazine, Latina Faculty Reshaping (February 27, 2012) http://anthropology.usf.edu/faculty/data/Feinberg2012-Latina_Faculty_Reshaping_Higher_Education_-_Iraida_Carrion1.pdf

2011 New York City Science and Engineering Fair (NYCSeF) Keynote Speaker at the American Museum of Natural History (And Opening Act for Impromptu visit from President Barack Obama http://nycsef.cuny.edu/2070/), 'Bitten by the Science Bug' (March 29, 2011) http://academicworks.cuny.edu/cc_pubs/355/.

2011 CUNY Lecture Series: The Science of Female Negotiation, Keynote Speaker Podcast (Dec 20, 2011) http://www1.cuny.edu/mu/podcasts/2011/12/20/the-science-of-female-negotiation/

2004 American Association for the Advancement of Science (AAAS) Lecture Series on Women in Science and Engineering, Travel Award-Winning Essay  http://academicworks.cuny.edu/cc_pubs/356/ also found on AAAS website: http://ehrweb.aaas.org/womeninscience/essays/vazquez.htm

Heading: 
Refereed Conference Proceedings
Description: 

EGFR-mediated Migration of Retinal Muller Glial Cells, J.Pena, N. Dulger and   M. Vazquez. Tissue Engineering-Undergraduate Poster Platform P-SAT-613, BMES Annual Meeting 2017 (October 11-14, AZ)

A multiscale Device for the Study of Compartmentalized Purinergic Signaling, S. McCutcheon, R. Majeska, M. Schaffler and M. Vazquez. Nano- and Micro-Technologies Poster Platform P-FRI-111, BMES Annual Meeting 2017 (October 11-14, Phoenix, AZ)

Electrochemical Stimulation to Enhance Retinal Progenitor Cell Migration and Integration into Damaged Retina, S. Mishra, S. Redenti and M. Vazquez. Cell Migration, Poster Platform P-TH-164, BMES Annual Meeting 2017 (October 11-14, Phoenix, AZ)

Utilizing Genetics and Microfluidics to Examine Neural Cell Migration in Retinogenesis of a Drosophila Model, C. Pena, S. Zhang, M., Kamara, T. Venkatesh and M. Vazquez. Cell Migration, Poster Platform P-TH-154, BMES Annual Meeting 2017 (October 11-14, Phoenix, AZ)

Chemotactic Response Properties of Photoreceptor Precursor and Retinal Progenitor Cells in Microfluidic-derived VEGF and Ostiopontin Gradients, O. Onwumere, M. Wong, B Kaur, S. Mishra, J. Mighty, M. Vazquez, and S. Redenti. NYSTEM Annual Meeting 2017 (May 11-12, 2017, NY, NY.) 

A Drosophila Model to Examine Collective Migration during Retinogenesis, C. Pena, S. Zhang, M. Kamara, T. Venkatesh, and  M. Vazquez, Research Posters in Biomedical Devices No 46, Northeast Bioengineering Conference 2017 (March 31-Apri 2, 2017, Newark, NJ) http://academicworks.cuny.edu/cc_pubs/368/

A nano-microfluidic Device for the study of Osteocyte Apoptotic Signaling, S. McCutcheon, M. Schaffer and M. Vazquez; Orthopaedic and Rehabilitation Engineering, Oral Platform, OP-Fri-2-17. BMES Annual Meeting 2016 (October 5-8, Minneapolis, MN)

Growth Factor Mediated Migration of Neonatal Schwann Cells (nnSC), T. Singh and M. Vazquez; Neural Engineering, Oral Platform Session OP-Sat-2-17, BMES Annual Meeting 2016 (October 5-8, Minneapolis, MN)

Electric-Chemotactic Fields Induce Cooperative Movement of Retinal Progenitor CellsS. Mishra, S. Redenti and M. Vazquez; Neural Engineering, Poster Platform Session, Th-118, BMES Annual Meeting 2016 (October 5-8, Minneapolis, MN) http://academicworks.cuny.edu/cc_pubs/358

Health Disparities in the Visual System: Research and EducationM. Vazquez (Invited speaker) Session Chair: Dr. Gilda Barabino; Engineering Low Cost Solutions to Address Health Care Disparities, Special Session, BMES Annual Meeting 2016 (October 5-8, Minneapolis, MN)

Chemotactic Migration of Clustered Central Nervous System Progenitor CellsS. McCutcheon, J. Uchenna, M. Vazquez, and S. Redenti; Cell Adhesion and Motility Poster Platform, P-Th-429, BMES Annual Meeting 2014 (October 22-24, San Antonio, TX) http://academicworks.cuny.edu/cc_pubs/340/

Epidermal Growth Factor as a New Migration-Targeted Therapy for Pediatric Brain Tumors, J. Rico, T. Singh, S. McCutcheon, and M. Vazquez; Microtechnologies for Cancer, Oral Platform Session OP-Sat-3-6, BMES Annual Meeting 2014 (October 22-24, San Antonio, TX)

Chemotactic Gradients to Induce Photoreceptor Transplantation, S. Mishra, J. Unachukwu, S. Redenti, and M. Vazquez, BioMEMS, Tissue and Organs on a Chip, Cell Behavior in Micro/Nano Devices Paperfluidics, Poster Platform, P-Th-554, BMES Annual Meeting 2014 (October 22-24, San Antonio, TX)

Carboxymethylcellulose Hydrogels Support CNS-derived Tumor Cell Chemotactic MigrationT. Singh, C. Kothapalli, D. Varma, S. Nicoll, and M. Vazquez; Biomaterials for Controlling Cell Environment, Poster Platform, P-Fri-152 BMES Annual Meeting 2014 (October 22-24, San Antonio, TX) http://academicworks.cuny.edu/cc_pubs/339/

Microfluidic Platforms Overview, M. Vazquez, Microfluidic Platforms I, Oral Platform Session OP-Thurs-1-12; BMES Annual Meeting 2014 (October 22-24, San Antonio, TX)

EGF as a New Therapeutic Target for Medulloblastoma MetastasisJ. Rico-Valera and M. Vazquez; Cell Motility Oral Platform, AP-057 SACNAS Annual Meeting 2014 (October 16-18, Los Angeles, CA)

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Selected Publications
Description: 

Pena J.; Dulger N.; Redenti, S.; Majeska R.; and Vazquez, M., ‘Controlled microenvironments to evaluate chemotactic properties of cultured Muller glia,' Experimental Eye Research (Accepted 5/2018)


Vazquez M., ‘Engaging Biomedical Engineering in Health Disparities Challenges,’ Journal of Community Medicine & Health Education, Accepted 03/2018.


Thakur A., Mishra S., Pena J., Zhou J., Redenti S., Majeska R., and Vazquez, M., ‘Collective adhesion and displacement of retinal progenitor cells upon extracellular matrix substrates of transplantable biomaterials,’ J. Tissue Eng. (2018) Vol. 9: 1–14.     http://journals.sagepub.com/doi/full/10.1177/2041731417751286.


Mishra S.; Vazquez, M., ‘A Gal-MµS device to evaluate cell migratory response to combined galvano-chemotactic fields,' Biosensors (Basel). 2017 Nov 21;7(4).  https://www.ncbi.nlm.nih.gov/pubmed/29160793


Vazquez M.; Marte O.; Barba J.; Hubbard K.; 'An approach to integrating health disparities within undergraduate biomedical engineering education,' Ann Biomed. Eng. 2017, Published Online August 28, 2017. http://rdcu.be/vl2n


McCutcheon S.; Majeska R.; Schaffler M.B.; Vazquez M., 'A multiscale fluidic device for the study of dendrite-mediated cell to cell communication.' Biomed Microdevices, 2017 Aug 8;19(3):71. 


Unachukwu, U.; Warren, A.; Zhou, J.;, Li, Z.;  Mishra, S.; Sauane, M.; Lim, H.; Vazquez, M.;  Redenti, S.; ‘Molecular signaling guiding photoreceptor precursor cell migration following transplantation into damaged retina,’ Nature Scientific Reports 2016 Mar 3;6:22392 http://academicworks.cuny.edu/cc_pubs/332/


McCutcheon S.; Unachukwu U, Thakur A, Majeska R, Redenti S, Vazquez M, ‘In Vitro Formation of Neuroclusters in Microfluidic Devices and Cell Migration as a Function of Stromal-Derived Growth Factor 1 Gradients.’ Cell Adh Migr. 2016 Jan 8:0. http://academicworks.cuny.edu/cc_pubs/342/


Beck C, Singh T, Farooqi A, Venkatesh T, Vazquez M., ‘Controlled microfluidics to examine growth-factor induced migration of neural progenitors in the Drosophila visual system,’ J Neurosci Methods. 2015 Dec 29;262:32-40. http://academicworks.cuny.edu/cc_pubs/359


Mishra S.; Thakur A.; Redenti S.; Vazquez M., A model microfluidics-based system for the human and mouse retina,’ Biomed Microdevices. 2015 Dec;17(6):107. http://academicworks.cuny.edu/cc_pubs/329/


Rico-Valera J.; Singh T.; McCutcheon S.; Vazquez M.,’EGF as a therapeutic target for medulloblastoma metastasis,’ Cell Mol Bioeng 2015 July 1; Volume 3, Issue 2, pp323. Cell Mol Bioeng. 2015 Dec;8(4):553-565 http://academicworks.cuny.edu/cc_pubs/349


Singh T, Kothapalli C, Varma D, Nicoll SB, Vazquez M, Carboxymethylcellulose hydrogels support central nervous system-derived tumor-cell chemotactic migration: Comparison with conventional extracellular matrix macromolecules J Biomater Appl. 2014 Sep;29(3):433-41. http://academicworks.cuny.edu/cc_pubs/347/


Unachukwu UJ, Sauane M, Vazquez M, Redenti S.; ‘Microfluidic Generated EGF-Gradients Induce Chemokinesis of Transplantable Retinal Progenitor Cells via the JAK/STAT and PI3Kinase Signaling Pathways,’ PLoS One. 2013 Dec 23;8(12) http://academicworks.cuny.edu/cc_pubs/330/


Dudu V., Able RA Jr.; Rotari, V.; Kong, Q.; Vazquez M., ' Role of Epidermal Growth Factor-triggered PI3K/Akt signaling in the Migration of Medulloblastoma-derived Cells,' Cell Mol Bioeng 2012 Dec 1; Volume 5, Issue 4, pp 402-413. http://academicworks.cuny.edu/cc_pubs/360


Able RA Jr.; Ngnabeuye, C.; Beck, C.; Holland, EC.; Vazquez M., 'Low Concentration Microenvironments Enhance the Migration of Neonatal Cells of Glial Lineage,' Cell Mol Bioeng. 2012 Dec 1; Volume 5, Issue 2, pp 128-142. http://academicworks.cuny.edu/cc_pubs/357


Dudu V.; Rotari V.; Vazquez M., 'Sendai Virus-based Liposomes Enable Targeted Cytosolic Delivery of Nanoparticles in Brain Tumor-Derived Cells,' J Nanobiotechnology. 2012 Feb 17;10:9. http://academicworks.cuny.edu/cc_pubs/350

Heading: 
Research Support
Description: 

 


       Photoreceptor integration via chemotactic honing, Principal Investigator: Maribel Vazquez, Sc.D.

National Eye Institute (5 R21 EY 026752) Supports development of microfluidics to examine photoreceptor chemotaxis


 STC: Emerging Behaviors of Integrated Biological Systems (EBICS), Principal Investigator: Kamm, Roger, Ph.D. (Subcontract PI: Maribel Vazquez, Sc.D.)                 

 National Science Foundation (CBET-0939511) Supports development of microfluidics to examine glial-neuronal interactions in vitro


A micro-retina system for progenitor migration, Principal Investigator: Maribel Vazquez, Sc.D.                                         

City University of New York (PSC-CUNY REG48) Supports development of a micro-retina microfluidic system


  A nano-osteo fluidic device to examine osteocyte apoptotic signaling, Principal Investigator: Maribel Vazquez, Sc.D.

City University of New York (ASRC Pilot Grant) Supports development of nanofluidics to examine signaling across dendritic cells


Systems Biology Approach to Tumorigenesis, Principal Investigator: Micor, Franziska, PhD   (Subcontract PI: Maribel Vazquez, Sc.D.)                                                  

National Cancer Institute (1 U54 CA143798-02) Supports use of microfluidics to identify EGF activation during in vitro migration of glioma


 

Heading: 
Administrative Leadership in Education
Description: 

BME Executive Committee Member, 2016-Present

Masters in Translational Medicine (MTM) Steering Committee and Engineering Faculty Advisor, 2015-Present

Accreditation Board for Engineering and Technology (ABET) BME Chair, 2014-2016

Undergraduate BME Curriculum Chair, 2010-2016

Founding Member of the BME Department, 2001-2006

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Courses Offered
Description: 

GRADUATE:

Microfluidics and Microfabrication (BME510/I7700) http://academicworks.cuny.edu/cc_oers/14

Capstone BioDesign for Masters in Translational Medicine I (BMEI6400)

Capstone BioDesign for Masters in Translational Medicine II (BMEI6500)

Capstone BioDesign for Masters in Translational Medicine III (BMEI6600)


UNDERGRADUATE:

Introduction to Biomedical Engineering (BME101) http://academicworks.cuny.edu/cc_oers/15

Experimental Methods in Biomedical Engineering (BME310) 

Capstone Senior Design I (BME450)

Capstone Senior Design II (BME460)


HIGH SCHOOL (Summer Only):

CUNY Summer STEM Institute Keynote Lecture 2016 http://academicworks.cuny.edu/cc_oers/13/

CUNY Summer STEM Institute: Experimental Research in Engineering (ERE) http://academicworks.cuny.edu/cc_oers/16


 

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