Hoau-yan Wang

Associate Medical Professor

Main Affiliation

Molecular, Cellular and Biomedical Sciences

Building

Center for Discovery and Innovation

Office

3.211

Phone

212-650-8813

Fax

212-650-7726

H_Wang

Hoau-yan Wang

Education

Ph.D., 1988, Medical College of Pennsylvania

M.S., 1985, St. John's University (NY)

B.S., 1981, China Medical College

Publications

Fontanesi C, Kvint S, Frazzitta G, Bera R, Ferrazzoli D, Di Rocco A, Rebholz H, Friedman E, Pezzoli G, Quartarone A, Wang HY, Ghilardi MF (2015) Intensive rehabilitation enhances lymphocyte BDNF-TrkB signaling in patients with Parkinson’s disease.  Neurorehabilition & Neuronal Repair  DOI: 10.1177/1545968315600272
 
Banerjee A, Wang HY, MacDonald ML, Borgmann-Winter KE, Stucky A, Kvasic J, Egbujo C, Talbot K, Hemby SE, Siegel SJ, Arnold SE, Gur RE, Hahn C-G (2015) Src hypoactivity is a convergent mechanism for NMDA receptor hypofunction in schizophrenia. Mol. Psychiatry  20:1091-1100 (doi:10.1038/mp.2014.115)  Jointed first authors
 
Yan H, Xu T, Lee K-C, Wang HY, Zhang Y (2013) Isoflurane increases neuronal cell death by downregulating miR-214. Plus One 8(2): e55276.
 
Wang HY, Bakshi K, Frankfurt M, Stucky A, Goberdhan M, Shah SM, Burns LH (2012) Reducing Amyloid-related Alzheimer’s disease pathogenesis by a small molecule targeting filamin A. J Neurosci 32(29): 9773-9784.
 
Talbot K, Wang HY, Kazi H, Han L-Y, Bakshi KP, Stucky A, Fuino RL, Kawaguchi KR, Samoyedny AJ, Wilson RS, Arvanitakis Z, Schneider JA, Wolf BA, Bennett DA, Trojanowski JQ, Arnold SE (2012) Brain insulin resistance demonstrated in Alzheimer’s disease without diabetes is associated with dyregulated IRS-1 and implicated in impaired cognition. J Clin Inv 122(4): 1-23.  co-first authors
 
Nagele RG, Clifford PM, Siu G, Levin EC, Acharya NK, Han M, Kosciuk MC, Venkataraman V, Zavareh S, Zarrabi S, Kinsler K, Patel N, Nagele EP, Dash J, Wang HY, Levitas A (2011) Brain-reactive autoantibodies prevalent in human sera increase intraneuronal Amyloid-1-42 deposition. J Alzheimers Dis 25: 605-622.
 
Wang HY, Crupi D, Liu J, Stucky A, Cruciata G, Di Rocco A, Friedman E, Quartarone A, Ghilardi MF (2011)  rTMS enhances BDNF-TrkB signaling in both brain and lymphocytes. J Neurosci 31: 11044-11054.
 
Wang HY, Stucky A, Hahn C-G, Wilson RS, Bennett DA, Arnold S (2011) BDNF-TrkB signaling in late life cognitive decline and Alzheimer's disease.  Translational Neurosci 2: 91-100.
 
Wang HY, Bakshi K, Shen C, Frankfurt M, Trocme-Thibierge C, Morain P (2010) S 24795 limits -amyloid - 7 nicotinic receptor interaction and reduces Alzheimer’s disease-like pathologies. Biol Psychiatry 67: 522-530.
 
Wang HY, Stucky A, Liu J, Shen C, Trocme-Thibierge C, Morain P (2009) Dissociating -amyloid from 7 nicotinic acetylcholine receptor by a novel therapeutic agent, S 24795 normalizes 7 nicotinic acetylcholine and NMDA receptor function in Alzheimer’s disease brain. J Neurosci 29: 10961-10973.