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Daniel Keedy

Faculty and Staff Profiles

Daniel Keedy

Assistant Professor

School/Division
Department
Office
ASRC 3.314
Building: 
ASRC
Phone Number: 
212-413-3246
Email: 
Daniel.Keedy@asrc.cuny.edu
Personal Website: 
http://www.keedylab.com
Photograph of Professor Keedy
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Profile
Description: 

Daniel Keedy is an Assistant Professor with the Structural Biology Initiative at the ASRC and the Department of Chemistry and Biochemistry at the City College of New York beginning January 8, 2018. Prior to his appointment, he was an AP Giannini Postdoctoral Fellow in Bioengineering and Therapeutic Sciences at the University of California, San Francisco working with Professor James Fraser. He earned his PhD in Biochemistry and Structural Biology & Biophysics from Duke University after receiving his BA in Biochemistry & Molecular Biology from Rhodes College. His research on protein structural flexibility, temperature-dependent X-ray crystallography, and allosteric regulation has led to over 15 publications in leading scientific journals and over ten presentations at a variety of scientific meetings.


 

Heading: 
Education
Description: 
A.P. Giannini Postdoctoral Fellow, University of California, San Francisco, 2012-2017
Ph.D., Duke University, 2006-2012
B.A., Rhodes College, 2002-2006
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Research Interests
Description: 

Professor Keedy develops experimental and computational methods to control proteins by biasing toward specific conformations that underlie functions such as allostery, ligand binding, and catalysis. His work reveals new opportunities to modulate the activities of therapeutic targets such as tyrosine phosphatases with small molecules and protein engineering, and also offers insights into more general evolutionary processes that led to functional diversity in the human genome.

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