Raymond S. Tu

Professor

Main Affiliation

Chemical Engineering

Areas of Expertise/Research

  • Biomolecules
  • Interfaces
  • Self-Assembly

Building

Steinman Hall

Office

T313

Phone

(212) 650-7031

Fax

(212) 650-6660

Prof Tu - ChE

Raymond S. Tu

Profile

Raymond Tu received his PhD in chemical engineering from the University of California - Santa Barbara in 2004, studying the design and self-assembly of peptide functionalized molecular architectures.  He completed a post-doctoral fellowship in 2005 at Georgia Institute of Technology investigating rheological properties of biologically functionalized polymer-based materials.  Currently, he is an associate professor in the Chemical Engineering Department at The City College of The City University of New York.  The focus of his research program is the synthesis of surface-active molecular building blocks, which are derived from the combination of elements that direct interfacial assembly with components responsible for selective binding.  This methodology is proving to be an effective tool for engineering complex composite materials that contain structures with multiple length-scales. 

 

Website: http://rtu.ccny.cuny.edu/

Education

University of Florida, BS 1998

University of California – Santa Barbara, PhD 2004

Georgia Institute of Technology, PostDoc

Publications

Recent publications:

 

Jung, Y., Khan, M. K., Podbevšek, D., Sudhakar, T., Tu, R. S., & Chen, X. “Enhanced water-responsive actuation of porous Bombyx mori silk.” Soft Matter, (2023) 19,11, 2047-2052.


Kanthe, Ankit D., et al. "Differential Surface Adsorption Phenomena for Conventional and Novel Surfactants Correlates with Changes in Interfacial mAb Stabilization." Molecular Pharmaceutics 19.9 (2022): 3100-3113

Kanthe, A., Ilott, A., Krause, M., Zheng, S., Li, J., Bu, W., Bera, M.K., Lin, B., Maldarelli, C., Tu, RS. No Ordinary Proteins: Adsorption and Molecular Orientation of Monoclonal Antibodies. Science Advances. 2021, 7(35):eabg2873. DOI: 10.1126/sciadv.abg2873.

Hu, J., Wang, J., Zhu, X., Tu, RS, Nanda, V., and Xu, F. Design Strategies to Tune the Structural and Mechanical Properties of Synthetic Collagen Hydrogels, Biomacromol. 2021, DOI: 10.1021/acs.biomac. 1c00520.

Jung, Y., Golru, S.S., Biddinger, E.J., Tu, RS, Chen, X. Tuning water-responsiveness with Bombyx mori silk–silica nanoparticle composites. Soft Matter 2021, 17 (34): 7817-7821. DOI:10.1039/D1SM00794G.

Park, Y, Jung, Y, Li, TD, Jianpei, L, Tu, RS, Chen X. -Sheet Nanocrystals Dictate Water Responsiveness of Bombyx Mori Silk. Macromol. Rapid Comm. (2020) 41, 7, 1900612 DOI: 10.1002/marc.201900612.

Kanthe AD, Krause ME, Zheng S, Ilott A, Li J, Bu W, Bera MK, Lin B, Maldarelli C, Tu RS. Armoring the interface with surfactant to prevent the adsorption of monoclonal antibody. ACS Appl. Mater. Interfaces, (2020) 12, 8, 9977–9988 DOI: 10.1021/acsami.9b21979

Knapp EM, Dagastine RR, Tu RS, Kretzschmar I, Effect of Orientation and Wetting Properties on the Behavior of Janus Particles at the Air-Water Interface, ACS Appl. Mater. Interfaces (2020) 12, 4, 5128-5135, https://doi.org/10.1021/acsami.9b21067

Razavi S, Lin B, Lee KY, Tu RS, Kretzschmar I. Impact of Surface Amphiphilicity on the Interfacial Behavior of Janus Particle Layers under Compression. Langmuir (2019) 35, 48, 15813-15824, https://doi.org/10.1021/acs.langmuir.9b01664

Li, J.; Krause, M. E.; Chen, X.; Cheng, Y.; Dai, W.; Hill, J. J.; Huang, M.; Jordan, S.; LaCasse, D.; Narhi, L., Tu, R.S. Interfacial Stress in the Development of Biologics: Fundamental Understanding, Current Practice, and Future Perspective. The AAPS journal 2019, 21, 44. DOI: 10.1208/s12248-019-0312-3

S.C., O'Neill, A.D. Kanthe, J.A. Weber, and R. S. Tu ‘Reverse’ Hofmeister effects on the sol-gel transition rates for an α-helical peptide-PEG bioconjugate Physical Chemistry Chemical Physics, (2018), 20, 20287-20295. DOI: 10.1039/C8CP03316A

 


BOOK/BOOK CHAPTERS

Nguyen, Hung and Tu, Raymond “Comprehensive Biomaterials: Chapter - Surface Engineering Using Amphiphilic Peptides” ISBN: 9780081006917, Elsevier, June 2017

 

Li, Jinjiang; Krause, Mary; Tu, Raymond (Approved book contract) “Protein Instability at Interfaces During Product Development: Fundamental Understanding, Evaluation, and Mitigation” Springer Nature 2020.