In 2017, Hari Akula, then a City College of New York graduate student, and his mentor, chemistry professor Mahesh Lakshman, published a facile approach to the modification of pyrimidine nucleosides. Their work, which has potential to yield compounds that inhibit the virus that causes AIDS, has now been accepted as a protocol in the field. It is the cover story in the current issue of “ Current Protocols in Nucleic Acid Chemistry.” In the natural sciences, a protocol is a predefined written procedural method in the design and implementation of experiments. Protocols are written whenever it is
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