Physics Colloquium, Dr. Philip S. Lukeman, Multiscale Polyvalent Biosensing using DNA Nanotechnology & Electrochemistry 

Dates
Wed, Mar 22, 2023 - 04:00 PM — Wed, Mar 22, 2023 - 05:00 PM
Admission Fee
Free
Event Address
Marshak, Room 418N and by Zoom. For more information please contact Prof. Sriram Ganeshan, sganeshan@ccny.cuny.edu
Event Details

Multiscale Polyvalent Biosensing using DNA Nanotechnology & Electrochemistry 

 

Dr. Philip S. Lukeman 
Associate Professor 
School of Liberal Arts and Sciences 
St. John’s University, Queens, NY 

 

Abstract: 

We will describe here the utilization of DNA nanotechnology to construct three different electrochemical biosensor platforms that can:  

  • Be used to detect a wide range of targets (DNA, proteins) by swapping independent, modular analyte binding domains and reporter domains  

  • Detect 100 nm+ scale targets and discriminate intact target vs subunit binding  

  • Utilize electron transfer rate as a measure of polyvalent binding 

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