Biochemistry Seminar: Andrei A. Korostelev, "The ribosome in action: uncovering translation and new stress sensing mechanisms by cryo-EM"

Dates
Wed, Oct 12, 2022 - 12:00 PM — Wed, Oct 12, 2022 - 01:00 PM
Admission Fee
Free. Coffee & tea will be available in the ASRC Cafe at 11:30 AM
Event Address
The speaker will be in-person:
ASRC Main Auditorium
85 Saint Nicholas Terrace
Current CUNY Cleared4 Pass is required for entrance; masks are optional.
Phone Number
212-650-8803
Event Location
The seminar can also be viewed via Zoom.
Zoom link: https://gc-cuny.zoom.us/j/4954048198?pwd=eVlkMFdHcjV6d3pkYzB4V2VtbHJGdz09
Event Details

Andrei A. Korostelev, Professor, RNA Therapeutics Institute University of Massachusetts Chan Medical School, will give a talk on "The ribosome in action: uncovering translation and new stress sensing mechanisms by cryo-EM."

ABSRACT

Ribosomes are a central hub for controlling gene expression. Not only do they synthesize proteins, but they potently respond to stress signals. Our lab addresses mechanistic questions concerning ribosome functions, such as: How does the ribosome accurately synthesize proteins? How does the ribosome sense cellular stresses? In my presentation, I will talk about our use of time-resolved cryo-EM and biochemistry to visualize how the ribosome accurately reads the genetic instructions encoded in mRNA and how stalled ribosomes can initiate profound changes in cellular pathways in response to stress. 

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