Bradley Hyman, MD, PhD, Professor, Department of Neurology, Harvard Medical School, Massachusetts General Hospital, will give a seminar on "Drivers of Heterogeneity in Alzheimer’s disease."

ABSTRACT

Although Alzheimer’s disease is classically thought of as one disease process, recent data give rise to an alternate view: that Alzheimer’s represents a common phenotype that is consequent of multiple molecular drivers.  In some ways this is analogous to cancer, where understanding the drivers of disease provides therapeutic insights not evident from classical pathology or from symptoms.  The lecture will explore how disease heterogeneity may well provide a tool to use to understand diverse biological drivers of an Alzheimer syndrome.