2016 - 2020

Publications from the year 2016 - 2020


  1. Photon Entanglement Through Brain Tissue, Lingyan Shi, Enrique J. Galvez, Robert R. Alfano, Scientific Reports | 6:37714 | (2016), DOI: 10.1038/srep37714.

  2. Generation of flower high-order Poincaré sphere laser beams from a spatial light modulator, T. H. Lu, T. D. Huang, J. G. Wang, L. W. Wang, R. R. Alfano, Sci. Rep. 6, 39657; doi: 10.1038/srep39657 (2016).

  3. Vulnerable atherosclerotic plaque detection by resonance Raman spectroscopy,Cheng-hui Liu, Susie Boydston-White, Arel Weisberg, Wubao Wang, Laura A. Sordillo, Adler Perotte, Vincent P. Tomaselli, Peter P. Sordillo, Zhe Pei, Lingyan Shi, Robert R. Alfano,  J. Biomed. Opt. 21(12), 127006 (2016), doi: 10.1117/1.JBO.21.12.127006.

  4. Terahertz spectroscopy of brain tissue from a mouse model of Alzheimer’s disese, Lingyan Shi, Pavel Shumyatsky,  Adrián Rodríguez-Contreras, and Robert Alfano, Journal of Biomedical Optics 21(1), 015014-5 (January 2016), 

  5. OPTICAL SOURCES A laser for complex spatial modes, Alfano, Robert R.; Milione, Giovanni; Galvez, Enrique J.; et al., Nature Photonics, Vol. 10, No. 5, 286-288  ( MAY 2016).

  6. Deep transmission of Laguerre-Gaussian vortex beams through turbid scattering media, Wang, W. B.; Gozali, Richard; Shi, Lingyan; et al., Optics Letters, Vol. 41, Issue:  9, 2069-2072 (May 1 2016).

  7. Slowing of Bessel light beam group velocity, Robert R. Alfano, Daniel A. Nolan, Optics Communications Vol. 361, 25–27,  February 2016, doi:10.1016/j.optcom.2015.10.016.

  8. Interface-state-phonon-assisted energy relaxation of hot electrons in CdSe quantum dots, Shengkun Zhang, Iosif Zeylikovich, Taposh K. Gayen, Bidyut Das, Robert R. Alfano, Aidong Shen, and Maria C. Tamargo Journal of Vacuum Science & Technology B 34, 02L107 (2016); doi: 10.1116/1.4941138

  9. Transmission in near-infrared optical windows for deep brain imaging, Lingyan Shi, Laura A. Sordillo, Adrián Rodríguez-Contreras, and Robert Alfano, J. Biophotonics 9, No. 1–2, 38–43 (2016) 


  1. Compact OAM microscope for edge enhancement of biomedical and object samples Richard Gozali, Thien-An Nguyen, Ethan Bendau, and Robert R. Alfano,  Review of Scientific Instruments 88, 093701 (2017); https://doi.org/10.1063/1.5000508.

  2. Propagation of Gaussian and Laguerre-Gaussian vortex beams through mouse brain tissue. Shi, L., Lindwasser, L., Wang, W., Alfano, R. and Rodríguez-Contreras, A. J. Biophotonics 1-5 (2017) 

  3. Label-Free Fluorescence Spectroscopy for Detecting Key Biomolecules in Brain Tissue from a Mouse Model of Alzheimer’s Disease, Lingyan Shi, Luyao Lu, George Harvey, Thomas Harvey, Adrián Rodríguez-Contreras & Robert R. Alfano, Scientific Reports 7, Article number: 2599 (2017), doi:10.1038/s41598-017-02673-5

  4. Alzheimer Mouse Brain Tissue Measured by Time Resolved Fluorescence Spectroscopy using Single- and Multi-Photon Excitation of Label Free Native Molecules, Bidyut Das, Lingyan Shi, Yury. Budansky, Adrian Rodriguez-Contreras, Robert Alfano, J. Biophotonics 1-8 (2017), doi:10.1002/jbio.201600318 

  5. Response to comments on “Slowing of Bessel light beam group velocity”, Robert R. Alfano, Daniel A. Nolan, Optics Communications Vol. 392, 302,  February 2017, doi:10.1016/j.optcom.2016.12.079.

  6. Hybrid generation and analysis of vector vortex beams, Sandra Mamani,  Ethan Bendau,  Jeff Secor, Solyman Ashrafi, Jiufeng J. Tu, Robert R. Alfano, Applied Optics, Vol. 56, No. 8, 2171 (2017).

  7. Short wavelength infrared optical windows for evaluation of benign and malignant tissues, Diana C. Sordillo, Laura A. Sordillo, Peter P. Sordillo, Lingyan Shi, Robert R. Alfano J. Biomed. Opt. 22(4), 045002 (2017), doi: 10.1117/1.JBO.22.4.045002.


  1. Evolution of the Supercontinuum LightSource, Robert Alfano, Lingyan Shi, Photonics Spectra, pp. 1-14, Jan 2018.

  2. Resonance Raman imaging for detecting and monitoring molecular pathological changes in human braon    tumors releated Warburg effect, Yan Zhou, Cheng-hui Liu, Chunyuan Zhang, Yang Yang, Xinguang Yu, Hailong Hu, Gangge Cheng, Binlin Wu, Lingyan Shi, Robert R. Alfano, Proc SPIE 10489, Optical Biopsy XVI: Toward Real- Time Spectroscopic Imaging and Diagnosis, 104891C (21st February 2018); doi: 10.1117/12.2290794

  3. Transmission of Classically Entangled Beams through Mouse Brain Tissue, Sandra Mamani, Lingyan Shi, Tahmid Ahmed, Romir Karnik, Adrián Rodríguez‐Contreras, Daniel Nolan, Robert Alfano, accepted for publication in Journal of Biophotonics, Volume11, issue12, e201800096, (2018). 

  4. Resonance Raman scattering of β-carotene solution excited by visible laser beams into second singlet state Luyao Lu, Lingyan Shib, Jeff Secor, Robert Alfano, Journal of Photochemistry & Photobiology, B: Biology 179 (2018) 18–22. https://doi.org/10.1016/j.jphotobiol.2017.12.022


  1. Optical Biopsy identification and grading of gliomas using ladel-free visible resonace Raman Spectroscopy,Journal of Biomedical Optics, Yan Zhou, Cheng-Hui Liu, Binlin Wu, Xinguang Yu, Gangge. Cheng,Ke Zhu, Kai Wang, Chunyuan Zhang Mingyue Zhao, Rui Zong, Lin Zhang, Lingyan shi, RobertAlfano, (2019), doi:10.1117/1.JBO.24.9.095001.

  2. Majorana Vortex Photons a Form of Entangled Photons Propagation through Brain tissue, Journal of Biophotonics, 2019 Robert Alfano, Sandra Mamani, Lingyan Shi, Daniel Nolan. Doi:10.1002/jbio.201900036.

  3. Twisted light transfers OAM and SAM to electrons in a GaAs photocathode, Robert Alfano, Laura A. Sordillo, Sandra Mamani, Mikhail Sharonov. Proc. SPIE 10935, complex Light and optical Forces XIII, 109351P (1st March 2019), doi: 10.1117/12.2514646

  4. Alzheimer’s disease: Label-free florescence showa increases in indoleamine 2, 3-dioxygenase (IDO) or tryptophan 2, 3-dioxygenase (TDO) activity in affected areas of the brain. Laura A. Sordillo, Lin Zhang, Robert Alfano, Peter P. Sordillo, Proc. SPIE 10873 Optical Boipsy XVII: Toward Real-Time spectroscopic Imaging and Diagnosis, 108731C (4th March 2019); doi: 10.1117/12.2513384

  5. Advances in medical applications using SWIR light in the wavelength range 1000 to 2500nm. Laura A. Sordillo, Lingyan Shi, Diana C. Sordillo, Peter P. Sordillo, Robert Alfano. Proc. SPIE 10873 10873 Optical Biosy XVII: Toward Real-Time spectroscopic Imaging and Diagnosis, 108730T (4th March 2019); doi 10.1117/12.2513382

  6. The interaction of twisted Lagurre-Gaussian light with a GaAs photocathode to investigate photogenerated polarizes electrons, Laura A. Sordillo, S. Mamani, M. Sharonov, R. R. Alfano, Applied Physics Letters 114,041104(2019); https://doi.org/10.1063/1.5078503

  7. A pilot study for distinguishing basel cell carcinoma from normal human skin tissues using visible resonance Raman Spectroscopy, Cheng-Hui-Liu, Zang, Sordillo, Beckman, Alfano, J cancer Metastasis Treat2019; 5:4. http://dx.doi.org/10.20517/2394-4722.2018.55

  8. Combined spatial frequency spectroscopy analysis with visible resonance Raman for optical of Human brain   metastases of the lung cancers, Yan Zhou, Cheng-Hui Liu, Yang Pu, Binlin Wu, Thien An Nguyen, Gangge Cheng, Lixin Zhou, Ke Zhu, Jun Chen Qingbo Li, Alfano Journal of Innovative optical Health Sciences, vol.12, No.2(2019) 1950010, DOI: 10.1142/S1793545819550010X