The Thomas Haines Memorial Seminar: Peter B. Moore, "Structural Biology: Past, Present and Future"
Peter B. Moore, Professor Emeritus, Department of Chemistry, Yale University, New Haven, CT, will give the annual Thomas Haines Memorial Seminar. His talk is titled "Structural Biology: Past, Present and Future."
This seminar will also be available by Zoom. Zoom link: https://gc-cuny.zoom.us/j/91607074885?pwd=3peeVNPa5kUJJ48m7lObDWLl3SQ1nz.1 ; Meeting ID 916 0707 4885. Passcode: ASRCccny
Please note:
* Full names must be used to be admitted to the Zoom meeting.
* The Zoom meeting will be closed and locked at 12:15 p.m., and no one will be able to enter the meeting after that time.
ABSTRACT
Between ~1950 and ~2010, X-ray crystallography was the experimental technique of choice for determining the structures of biological macromolecules at atomic resolution. It is no longer. Around 2012, following a long gestation, electron microscopy emerged as a serious competitor, and about a decade later, AI-based computational methods were developed that can accurately predict the structure of almost any protein of known sequence. These developments have completely transformed the landscape of the discipline known as structural biology. The speaker will present his view of how the field of structural biology has evolved, and what it has taught us. He will also discuss some of the issues he thinks will need to be addressed if the field is to thrive.